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BIO Protocol

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A new home for Decentralized Biotech. Co-own the medicines of the future.
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Fund, learn, use. Bio is building rails to modernize how biomedical science reaches the real world: • Bio Protocol: fund research, build communities, go lab → market • BioAgents: AI scientists surface what works, for whom and why • Biofy: commerce layer turns research into real, shippable products Digital rails for accelerated scientific production. From lab to shelf exponentially cheaper and faster. Ship science in 2026.
Fund, learn, use.

Bio is building rails to modernize how biomedical science reaches the real world:

• Bio Protocol: fund research, build communities, go lab → market
• BioAgents: AI scientists surface what works, for whom and why
• Biofy: commerce layer turns research into real, shippable products

Digital rails for accelerated scientific production.

From lab to shelf exponentially cheaper and faster.

Ship science in 2026.
What if the research you heard about on Huberman or saw on Reddit could be openly validated, productized, and delivered to your door? Announcing Biofy. A Shopify for research-backed health products: http://shop.bio.xyz For decades, advanced biology has been locked behind institutions: slow to translate, hard to verify, disconnected from everyday health decisions. Consumers are often left navigating opaque marketplaces cluttered with big claims and little visibility. Biofy is a marketplace for health products with clear sourcing, visible lab data and direct access to the researchers and early adopters behind each product. Every product traced back to the labs and communities that shaped it - using DeSci to make provenance visible. → The vision: A place to explore your biology on your own terms, with products that are credible, accessible & transparently validated. • Digital provenance verifies lab tests & clinical data underlying each product • Engaged communities speed up R&D cycles providing real-time feedback • Funding flows to consumer validation, not ad spend → The goal: connect scientific research, product development and capital formation into a single growth loop. → First Product Live: Moon & Sol Drops by DermaDAO • Vitamin C + ferulic acid formula based on research from Fu-Hsiung Lin (Duke University) • Buy w/ a credit card or crypto & earn BioXP on every purchase toward Derma's $SKIN • Be early: BioXP per bottle reduced after 300 bottles sold More products dropping in time for the post-holidays wellness wave. DeSci is getting real. Real products, real-world assets, real onchain revenue. It’s time to bridge frontier research into lived experience. From open science, to your body.
What if the research you heard about on Huberman or saw on Reddit could be openly validated, productized, and delivered to your door?

Announcing Biofy.

A Shopify for research-backed health products: http://shop.bio.xyz

For decades, advanced biology has been locked behind institutions: slow to translate, hard to verify, disconnected from everyday health decisions.

Consumers are often left navigating opaque marketplaces cluttered with big claims and little visibility.

Biofy is a marketplace for health products with clear sourcing, visible lab data and direct access to the researchers and early adopters behind each product.

Every product traced back to the labs and communities that shaped it - using DeSci to make provenance visible.

→ The vision: A place to explore your biology on your own terms, with products that are credible, accessible & transparently validated.

• Digital provenance verifies lab tests & clinical data underlying each product
• Engaged communities speed up R&D cycles providing real-time feedback
• Funding flows to consumer validation, not ad spend

→ The goal: connect scientific research, product development and capital formation into a single growth loop.

→ First Product Live: Moon & Sol Drops by DermaDAO

• Vitamin C + ferulic acid formula based on research from Fu-Hsiung Lin (Duke University)
• Buy w/ a credit card or crypto & earn BioXP on every purchase toward Derma's $SKIN
• Be early: BioXP per bottle reduced after 300 bottles sold

More products dropping in time for the post-holidays wellness wave.

DeSci is getting real.
Real products, real-world assets, real onchain revenue.

It’s time to bridge frontier research into lived experience.
From open science, to your body.
How to achieve 10x exposure within 30 days of new token launches BioXP is designed to reward early, aligned participation rather than passive holding or late speculation. Access and upside are earned through ecosystem commitment, not timing hype. New ecosystem tokens receive an *elevated XP multiplier* during their first 30 days live. During this window, BioXP earned from staking new tokens is boosted by 10x, giving early participation significantly more weight. At the same time, users earn an additional multiplier based on their veBIO level. The more BIO a participant stakes and locks, the higher their earning power across ecosystem tokens, scaling up to a 10x level multiplier. In practice, BioXP earned follows a simple rule: Token base multiplier × level multiplier × value staked in USD During the first 30 days, these multipliers stack. For highly aligned participants, this can translate into up to a 100x XP boost relative to baseline conditions. The system is intentionally asymmetric. Early alignment compounds. Late participation still works, but the leverage belongs to those who show up first. If you want exposure during this early window, staking HOLI is the way to participate right now!
How to achieve 10x exposure within 30 days of new token launches

BioXP is designed to reward early, aligned participation rather than passive holding or late speculation. Access and upside are earned through ecosystem commitment, not timing hype.

New ecosystem tokens receive an *elevated XP multiplier* during their first 30 days live. During this window, BioXP earned from staking new tokens is boosted by 10x, giving early participation significantly more weight.

At the same time, users earn an additional multiplier based on their veBIO level. The more BIO a participant stakes and locks, the higher their earning power across ecosystem tokens, scaling up to a 10x level multiplier.

In practice, BioXP earned follows a simple rule:

Token base multiplier × level multiplier × value staked in USD

During the first 30 days, these multipliers stack. For highly aligned participants, this can translate into up to a 100x XP boost relative to baseline conditions.

The system is intentionally asymmetric. Early alignment compounds. Late participation still works, but the leverage belongs to those who show up first.

If you want exposure during this early window, staking HOLI is the way to participate right now!
🚨 Bio's Next Ignition Sale: @dermadao $SKIN sale begins this TUESDAY Dec 23. Get your BioXP ready to participate. Learn more about DermaLabs: https://app.bio.xyz/launchpad/DermaLabs
🚨 Bio's Next Ignition Sale: @dermadao

$SKIN sale begins this TUESDAY Dec 23.

Get your BioXP ready to participate.

Learn more about DermaLabs: https://app.bio.xyz/launchpad/DermaLabs
Highlights from the Biosphere🧪 • Bio launching a “Shopify” for science-backed products • DeSci Abu Dhabi features Sam Altman–backed Retro Biosciences • Next Ignition Sale TUESDAY: Cardio vs Weights brain health trial • AI Scientist Benchmarks Read the full weekly report: https://x.com/BioProtocol/status/2000219793861816406
Highlights from the Biosphere🧪

• Bio launching a “Shopify” for science-backed products
• DeSci Abu Dhabi features Sam Altman–backed Retro Biosciences
• Next Ignition Sale TUESDAY: Cardio vs Weights brain health trial
• AI Scientist Benchmarks

Read the full weekly report: https://x.com/BioProtocol/status/2000219793861816406
How does DeSci bring science to consumers faster? At DeSci Abu Dhabi, @paulkhls announced that Bio is building a ’Shopify’ for science-backed health products. DeSci’s edge: > Community-driven feedback & development bring science to market faster > Token incentives scale organic demand > BioAgents drive personalization & consumer discovery Initial featured products will include @Dermadao skin care, @HairDAO_ hair-loss treatments, @Cerebrum_DAO brain health supplement & more. More soon!
How does DeSci bring science to consumers faster?

At DeSci Abu Dhabi, @paulkhls announced that Bio is building a ’Shopify’ for science-backed health products.

DeSci’s edge:
> Community-driven feedback & development bring science to market faster
> Token incentives scale organic demand
> BioAgents drive personalization & consumer discovery

Initial featured products will include @Dermadao skin care, @HairDAO_ hair-loss treatments, @Cerebrum_DAO brain health supplement & more.

More soon!
Joe Betts-LaCroix, CEO of Sam Altman-backed longevity startup Retro Biosciences, joined DeSci Abu Dhabi as a surprise guest to discuss AI's growing influence on biomedical research: "Biology is too hard for human scientists alone." "There are around 20,000 human genes whose protein networks can generate on the order of 1M possible structural moieties. The best Harvard scientists specialize in only around 40." Retro Biosciences recently worked with Open AI to create GPT-4b (b for "bio') aimed at uncovering biological insights and inventions which humans can't create on their own. The model was used to uncover novel variants of the Yamanaka factors which achieve a 50x increase in reprogramming efficiency in vitro. "The tools are here," Joe said. "Speed is the mantra. Regulatory infrastructure can slow things down, so we're looking to venues where people are innovating particularly on regulatory frameworks and human trials."
Joe Betts-LaCroix, CEO of Sam Altman-backed longevity startup Retro Biosciences, joined DeSci Abu Dhabi as a surprise guest to discuss AI's growing influence on biomedical research:

"Biology is too hard for human scientists alone."

"There are around 20,000 human genes whose protein networks can generate on the order of 1M possible structural moieties. The best Harvard scientists specialize in only around 40."

Retro Biosciences recently worked with Open AI to create GPT-4b (b for "bio') aimed at uncovering biological insights and inventions which humans can't create on their own.

The model was used to uncover novel variants of the Yamanaka factors which achieve a 50x increase in reprogramming efficiency in vitro.

"The tools are here," Joe said. "Speed is the mantra. Regulatory infrastructure can slow things down, so we're looking to venues where people are innovating particularly on regulatory frameworks and human trials."
DeSci Abu Dhabi is ON! Exploring the next era of AI + biology, neuroscience, genetic engineering and longevity with speakers from Bio, @molecule_sci, @MIT, @EnhancedGames, @bnbchain, @Xtalpi & more! Join us for a full day of talks and watch the live stream - https://x.com/BioProtocol/status/1998637762455765093?s=20
DeSci Abu Dhabi is ON!

Exploring the next era of AI + biology, neuroscience, genetic engineering and longevity with speakers from Bio, @molecule_sci, @MIT, @EnhancedGames, @bnbchain, @Xtalpi & more!

Join us for a full day of talks and watch the live stream - https://x.com/BioProtocol/status/1998637762455765093?s=20
James Magnussen will be kicking off DeSci Abu Dhabi TOMORROW! An Olympian swimmer turned ‘enhanced athlete’, James will share his journey into Enhanced Games and how science is reshaping human limits. When: 10:20 AM GST / 6:20 AM UTC Where: Cleveland Clinic RSVP here: https://luma.com/DeSciAbuDhabi2025
James Magnussen will be kicking off DeSci Abu Dhabi TOMORROW!

An Olympian swimmer turned ‘enhanced athlete’, James will share his journey into Enhanced Games and how science is reshaping human limits.

When: 10:20 AM GST / 6:20 AM UTC
Where: Cleveland Clinic

RSVP here: https://luma.com/DeSciAbuDhabi2025
Last week in the Biosphere 🧪🌐 • Bio is expanding to @BNBCHAIN • @Aubrai_ BioAgent gets Deep Research • Biotech 2.0 workshop w/ @CompoundVC • DeSci Abu Dhabi • New framework for benchmarking Scientific AI Read the full weekly update: https://x.com/BioProtocol/status/1997781828850119073
Last week in the Biosphere 🧪🌐

• Bio is expanding to @BNBCHAIN
• @Aubrai_ BioAgent gets Deep Research
• Biotech 2.0 workshop w/ @CompoundVC
• DeSci Abu Dhabi
• New framework for benchmarking Scientific AI

Read the full weekly update:
https://x.com/BioProtocol/status/1997781828850119073
"The journey from an early conception to a drug being sold in pharmacies can take ten years or more and cost up to two billion dollars. DeSci is about bringing actual products to market far sooner." @paulkhls at Binance Blockchain Week, moderated by @samikhojali from BNB Chain.
"The journey from an early conception to a drug being sold in pharmacies can take ten years or more and cost up to two billion dollars. DeSci is about bringing actual products to market far sooner."

@paulkhls at Binance Blockchain Week, moderated by @samikhojali from BNB Chain.
See original
https://luma.com/DeSciAbuDhabi2025
https://luma.com/DeSciAbuDhabi2025
BIO Protocol
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🧪 5 days until DeSci comes to Abu Dhabi

Hear from an award-winning MIT neuroscientist, an Olympian turned "enhanced" athlete, stem cell geneticists pushing boundaries in human regeneration and biotech investors shaking up science finance.

See the full schedule & RSVP below↓
🧪 5 days until DeSci comes to Abu Dhabi Hear from an award-winning MIT neuroscientist, an Olympian turned "enhanced" athlete, stem cell geneticists pushing boundaries in human regeneration and biotech investors shaking up science finance. See the full schedule & RSVP below↓
🧪 5 days until DeSci comes to Abu Dhabi

Hear from an award-winning MIT neuroscientist, an Olympian turned "enhanced" athlete, stem cell geneticists pushing boundaries in human regeneration and biotech investors shaking up science finance.

See the full schedule & RSVP below↓
Live on stage TOMORROW ! at @binance Blockchain Week Paul Kohlhass and Christian Angermayer will sit down for a fireside chat discussing how AI, biotech and crypto are converging to unlock new scientific breakthroughs and funding models. 🔸December 4th at 12:15PM GST/UTC+4 🔸Main Stage
Live on stage TOMORROW ! at @binance Blockchain Week

Paul Kohlhass and Christian Angermayer will sit down for a fireside chat discussing how AI, biotech and crypto are converging to unlock new scientific breakthroughs and funding models.

🔸December 4th at 12:15PM GST/UTC+4

🔸Main Stage
You can now trade $BIO on BNB via @PancakeSwap, with more Bio ecosystem tokens being bridged in the coming weeks. BIO token on BNB: 0x226a2fa2556c48245e57cd1cba4c6c9e67077dd2 Stay tuned for upcoming launches on BNB
You can now trade $BIO on BNB via @PancakeSwap, with more Bio ecosystem tokens being bridged in the coming weeks. BIO token on BNB: 0x226a2fa2556c48245e57cd1cba4c6c9e67077dd2 Stay tuned for upcoming launches on BNB
BIO Protocol
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DeSci is coming to @BNBCHAIN
🧪

$BIO is now tradable on BNB, with more DeSci tokens coming.

This paves the way for Bio's Launchpad & x402-enabled BioAgents on BNB.

Bio is building a full-stack solution for DeSci builders and research communities to 100X the speed of science.

You can now trade $BIO on BNB via @PancakeSwap, with more Bio ecosystem tokens being bridged in the coming weeks.

BIO token on BNB: 0x226a2fa2556c48245e57cd1cba4c6c9e67077dd2

Stay tuned for upcoming launches on BNB
🔸

See the Bio on BNB roadmap

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DeSci is coming to @BNBCHAIN 🧪 $BIO is now tradable on BNB, with more DeSci tokens coming. This paves the way for Bio's Launchpad & x402-enabled BioAgents on BNB. Bio is building a full-stack solution for DeSci builders and research communities to 100X the speed of science. You can now trade $BIO on BNB via @PancakeSwap, with more Bio ecosystem tokens being bridged in the coming weeks. BIO token on BNB: 0x226a2fa2556c48245e57cd1cba4c6c9e67077dd2 Stay tuned for upcoming launches on BNB 🔸 See the Bio on BNB roadmap --------
DeSci is coming to @BNBCHAIN
🧪

$BIO is now tradable on BNB, with more DeSci tokens coming.

This paves the way for Bio's Launchpad & x402-enabled BioAgents on BNB.

Bio is building a full-stack solution for DeSci builders and research communities to 100X the speed of science.

You can now trade $BIO on BNB via @PancakeSwap, with more Bio ecosystem tokens being bridged in the coming weeks.

BIO token on BNB: 0x226a2fa2556c48245e57cd1cba4c6c9e67077dd2

Stay tuned for upcoming launches on BNB
🔸

See the Bio on BNB roadmap

--------
Bio Season 2: Building the Future of Permissionless DeSciIt’s time for Bio to evolve from a curated launchpad into a factory for decentralized biotech. Season 1 of the Bio Launchpad generated a wealth of data and learnings across our first project launches. Over 8,000 participants funded innovations in stem cell research, men’s health, psychedelic science & more. But despite the traction, it quickly became clear that Season 1 was not designed for scale or sustainability. Mercenary capital rotated from one sale to another, dumping their allocations post launch.Pairing new project tokens with BIO out of the gate tied network stability to volatile new assets.BioXP incentives skewed too heavily toward short-term participants, reducing the incentive to hold and stake $BIO, the lifeblood of the system.Research funding from trading fees didn’t meet the fundraising needs of biotech founders, undermining efforts to attract world-leading researchers and builders. We realized if we want Bio to truly change how scientific research gets funded globally, we needed a new model. Enter Bio Season 2 - engineered to launch and grow a new generation of billion-dollar biotech innovations. The upgrade rebalances power across the ecosystem - transforming Bio into a scalable engine for scientific discovery, where founders access sustainable funding, stakers earn long-term yield, and breakthroughs compound value across the network. The next phase: a permissionless factory for decentralized biotech. Key Upgrades: ASSET/USDC pools: New tokens are paired in pools with USDC, not BIO; ASSET/BIO pools are only added for successful projects that hit and sustain a target FDV.More XP for BIO stakers: We’ve implemented a formula that heavily rewards veBIO (locked BIO) - effectively giving BIO stakers a larger share of XP, especially as more ecosystem tokens are staked.Ecosystem Airdrops: Every new project will airdrop a percentage of its token supply to BIO stakers as a form of passive yield. (Planned to launch after the first wave of Season 2.)Limit-Sell Fundraising: Projects only unlock funding as they achieve market traction. Token sales are automatically executed via limit orders once a project’s FDV remains above preset thresholds, aligning fundraising with real growth.Instant BioXP: Users who need BioXP on short notice will be able to stake and lock BIO to get XP instantly, minus a fast track fee. This provides immediate access to ongoing sales while still locking up BIO. (Planned to launch after the first wave of Season 2.)Aerodrome Pools: All new tokens will launch their liquidity on Aerodrome (via USDC pools), enabling eligible assets to be tradeable on Coinbase from day one.x402 x BioAgents: We’re open-sourcing the BioAgents framework and integrating it with Coinbase’s x402 payments protocol. This will allow DeSci agents to transact seamlessly with each other and with humans, powering onchain agentic commerce across research and health use-cases.BNB Chain Bridge: The BIO token is being bridged to the BNB Chain, extending Bio’s reach into the BNB ecosystem and paving the way for other ecosystem assets to be bridged as well. The upgraded BioXP formula for BIO stakers will be pushed live in the coming days – meaning going forward, the system will heavily favor BIO stakers. ➤ Stake BIO now to start accumulating BioXP for the next wave of Ignition Sales in Bio Season 2. I. Launch & Early Trading USDC/ASSET Pools After a successful Ignition Sale, newly launched tokens will be paired in an AMM with USDC, instead of BIO. By adding USDC for initial liquidity, we remove the risk of an under-performing token dragging down BIO’s price.Successful assets get an ASSET/BIO pool only once they sustain above a pre-set FDV.This design also allows for tokens to be launched permissionlessly on Bio with ASSET/USDC pools, shielding BIO holders during a project’s volatile early days until it proves it can generate value for the network. The result: more assets, more scientific domains, more shots on goal to drive value to the ecosystem. Ecosystem Airdrops Every Ignition Sale distributes a percentage of the token’s initial supply to BIO stakers, creating a passive form of yield for BIO stakers.Note: Ecosystem airdrops are slated to go live after the first wave of Season 2 launches. Aerodrome Pool Launcher New tokens on Bio will launch their ASSET/USDC pool on Aerodrome, using its new pool launcher.Through the integration, any eligible token launching on Bio will trade on Coinbase on day one, expanding accessibility and liquidity. II. Tokenomics & Fundraising Limit-Sell Fundraising Instead of raising a lump sum upfront or relying solely on trading fees, projects unlock funding as they achieve market traction around valuation targets.A percentage of each project’s token supply is reserved to be sold gradually as the project’s market value grows.Sales are made via transparent DEX limit orders once the project’s valuation remains above certain FDV thresholds, continuing to sell incrementally as the token achieves higher valuation milestones. The result: Project teams receive proceeds only when real market traction occurs, aligning incentives between projects and their token holders. Project token sales are executed automatically and transparently as the project grows. Vesting To encourage stability post-launch, Ignition Sale participants get 20% of their tokens liquid at TGE, while the remaining 80% vests linearly over the next 30 days.By aligning everyone through a brief vesting period, Season 2 aims to create a more stable early market and discourages quick-flip behavior. III. BioXP BIO Staking Rewards Increase Staking BIO now yields a much larger share of BioXP compared to staking ecosystem tokens and other ecosystem activities.In addition, a portion of the total amount of XP generated by ecosystem staking and other activities is redistributed pro rata to BIO stakers. Meaning, the more ecosystem tokens staked on Bio, the more XP BIO stakers collectively earn, connecting network activity with rewards for BIO holders. Flexible Multipliers for Ecosystem Token Staking Each ecosystem token can have its XP reward multiplier adjusted individually.This lets the Bio community boost incentives for staking certain tokens - for instance, in a new token’s early days post-launch to bootstrap growth. Increased Max Allocation To accommodate stronger conviction and larger capital allocators, users can now purchase up to 1% of a token’s initial supply during its Ignition Sale, up from the previous 0.5% per user max allocation in Season 1.This upgrade allows for deeper liquidity and commitment from larger backers at the token’s inception. Instant BioXP What if you discover a live Ignition Sale late and don’t have the BioXP to participate? Season 2 introduces Instant BioXP to solve this.Users can stake BIO, and lock it for a period of time to instantly receive the XP for that timeframe, minus a fast track fee, to use on a live sale.This feature ensures anyone who wants to participate in a sale, including newcomers, a way to jump into a sale immediately, while still bolstering long-term BIO staking.Example: suppose staking a given amount of BIO locked for 2 weeks normally earns you 100 XP; with Instant BioXP, you might stake that BIO and get 60 XP instantly, effectively paying a 40 XP fee for the right to immediately get the XP and use it in a live sale.Note: Instant BioXP is planned to go live after the first wave of Season 2 launches. IV. Other Changes x402 x BioAgents We’re releasing a new open-source version of the BioAgents framework compatible with Coinbase’s x402 payment protocol.This means autonomous science agents in the Bio ecosystem will be able to transact via x402, whether it’s agent-to-agent or agent-to-human payments.A BioAgent could autonomously pay for services like hypothesis evaluation or access to datasets, or sell its analytical outputs, all using onchain x402 transactions. This integration paves the way for a new era of agent-driven commerce in scientific research. Binance Smart Chain Bridge We are building a bridge to connect BIO to Binance Smart Chain, allowing BIO to move into Binance’s ecosystem.This creates an entry point for BSC users and liquidity to flow into Bio, and vice versa.In time, we’ll also establish pathways for other Bio ecosystem tokens to bridge to BSC. Discoveries at machine speed. Season 2 is how Bio scales DeSci to the world. Science should be open. Capital should be agile. Access should be earned. ➤ Stake BIO now to stack BioXP and get ready for the first wave of Season 2 Sales. Coming soon!

Bio Season 2: Building the Future of Permissionless DeSci

It’s time for Bio to evolve from a curated launchpad into a factory for decentralized biotech.
Season 1 of the Bio Launchpad generated a wealth of data and learnings across our first project launches. Over 8,000 participants funded innovations in stem cell research, men’s health, psychedelic science & more.
But despite the traction, it quickly became clear that Season 1 was not designed for scale or sustainability.
Mercenary capital rotated from one sale to another, dumping their allocations post launch.Pairing new project tokens with BIO out of the gate tied network stability to volatile new assets.BioXP incentives skewed too heavily toward short-term participants, reducing the incentive to hold and stake $BIO, the lifeblood of the system.Research funding from trading fees didn’t meet the fundraising needs of biotech founders, undermining efforts to attract world-leading researchers and builders.
We realized if we want Bio to truly change how scientific research gets funded globally, we needed a new model.
Enter Bio Season 2 - engineered to launch and grow a new generation of billion-dollar biotech innovations. The upgrade rebalances power across the ecosystem - transforming Bio into a scalable engine for scientific discovery, where founders access sustainable funding, stakers earn long-term yield, and breakthroughs compound value across the network.


The next phase: a permissionless factory for decentralized biotech.
Key Upgrades:
ASSET/USDC pools: New tokens are paired in pools with USDC, not BIO; ASSET/BIO pools are only added for successful projects that hit and sustain a target FDV.More XP for BIO stakers: We’ve implemented a formula that heavily rewards veBIO (locked BIO) - effectively giving BIO stakers a larger share of XP, especially as more ecosystem tokens are staked.Ecosystem Airdrops: Every new project will airdrop a percentage of its token supply to BIO stakers as a form of passive yield. (Planned to launch after the first wave of Season 2.)Limit-Sell Fundraising: Projects only unlock funding as they achieve market traction. Token sales are automatically executed via limit orders once a project’s FDV remains above preset thresholds, aligning fundraising with real growth.Instant BioXP: Users who need BioXP on short notice will be able to stake and lock BIO to get XP instantly, minus a fast track fee. This provides immediate access to ongoing sales while still locking up BIO. (Planned to launch after the first wave of Season 2.)Aerodrome Pools: All new tokens will launch their liquidity on Aerodrome (via USDC pools), enabling eligible assets to be tradeable on Coinbase from day one.x402 x BioAgents: We’re open-sourcing the BioAgents framework and integrating it with Coinbase’s x402 payments protocol. This will allow DeSci agents to transact seamlessly with each other and with humans, powering onchain agentic commerce across research and health use-cases.BNB Chain Bridge: The BIO token is being bridged to the BNB Chain, extending Bio’s reach into the BNB ecosystem and paving the way for other ecosystem assets to be bridged as well.
The upgraded BioXP formula for BIO stakers will be pushed live in the coming days – meaning going forward, the system will heavily favor BIO stakers.
➤ Stake BIO now to start accumulating BioXP for the next wave of Ignition Sales in Bio Season 2.


I. Launch & Early Trading
USDC/ASSET Pools
After a successful Ignition Sale, newly launched tokens will be paired in an AMM with USDC, instead of BIO. By adding USDC for initial liquidity, we remove the risk of an under-performing token dragging down BIO’s price.Successful assets get an ASSET/BIO pool only once they sustain above a pre-set FDV.This design also allows for tokens to be launched permissionlessly on Bio with ASSET/USDC pools, shielding BIO holders during a project’s volatile early days until it proves it can generate value for the network.
The result: more assets, more scientific domains, more shots on goal to drive value to the ecosystem.
Ecosystem Airdrops
Every Ignition Sale distributes a percentage of the token’s initial supply to BIO stakers, creating a passive form of yield for BIO stakers.Note: Ecosystem airdrops are slated to go live after the first wave of Season 2 launches.
Aerodrome Pool Launcher
New tokens on Bio will launch their ASSET/USDC pool on Aerodrome, using its new pool launcher.Through the integration, any eligible token launching on Bio will trade on Coinbase on day one, expanding accessibility and liquidity.
II. Tokenomics & Fundraising
Limit-Sell Fundraising
Instead of raising a lump sum upfront or relying solely on trading fees, projects unlock funding as they achieve market traction around valuation targets.A percentage of each project’s token supply is reserved to be sold gradually as the project’s market value grows.Sales are made via transparent DEX limit orders once the project’s valuation remains above certain FDV thresholds, continuing to sell incrementally as the token achieves higher valuation milestones.
The result: Project teams receive proceeds only when real market traction occurs, aligning incentives between projects and their token holders.



Project token sales are executed automatically and transparently as the project grows.
Vesting
To encourage stability post-launch, Ignition Sale participants get 20% of their tokens liquid at TGE, while the remaining 80% vests linearly over the next 30 days.By aligning everyone through a brief vesting period, Season 2 aims to create a more stable early market and discourages quick-flip behavior.
III. BioXP
BIO Staking Rewards Increase
Staking BIO now yields a much larger share of BioXP compared to staking ecosystem tokens and other ecosystem activities.In addition, a portion of the total amount of XP generated by ecosystem staking and other activities is redistributed pro rata to BIO stakers. Meaning, the more ecosystem tokens staked on Bio, the more XP BIO stakers collectively earn, connecting network activity with rewards for BIO holders.
Flexible Multipliers for Ecosystem Token Staking
Each ecosystem token can have its XP reward multiplier adjusted individually.This lets the Bio community boost incentives for staking certain tokens - for instance, in a new token’s early days post-launch to bootstrap growth.
Increased Max Allocation
To accommodate stronger conviction and larger capital allocators, users can now purchase up to 1% of a token’s initial supply during its Ignition Sale, up from the previous 0.5% per user max allocation in Season 1.This upgrade allows for deeper liquidity and commitment from larger backers at the token’s inception.
Instant BioXP
What if you discover a live Ignition Sale late and don’t have the BioXP to participate? Season 2 introduces Instant BioXP to solve this.Users can stake BIO, and lock it for a period of time to instantly receive the XP for that timeframe, minus a fast track fee, to use on a live sale.This feature ensures anyone who wants to participate in a sale, including newcomers, a way to jump into a sale immediately, while still bolstering long-term BIO staking.Example: suppose staking a given amount of BIO locked for 2 weeks normally earns you 100 XP; with Instant BioXP, you might stake that BIO and get 60 XP instantly, effectively paying a 40 XP fee for the right to immediately get the XP and use it in a live sale.Note: Instant BioXP is planned to go live after the first wave of Season 2 launches.
IV. Other Changes
x402 x BioAgents
We’re releasing a new open-source version of the BioAgents framework compatible with Coinbase’s x402 payment protocol.This means autonomous science agents in the Bio ecosystem will be able to transact via x402, whether it’s agent-to-agent or agent-to-human payments.A BioAgent could autonomously pay for services like hypothesis evaluation or access to datasets, or sell its analytical outputs, all using onchain x402 transactions.
This integration paves the way for a new era of agent-driven commerce in scientific research.
Binance Smart Chain Bridge
We are building a bridge to connect BIO to Binance Smart Chain, allowing BIO to move into Binance’s ecosystem.This creates an entry point for BSC users and liquidity to flow into Bio, and vice versa.In time, we’ll also establish pathways for other Bio ecosystem tokens to bridge to BSC.



Discoveries at machine speed.
Season 2 is how Bio scales DeSci to the world.
Science should be open. Capital should be agile. Access should be earned.
➤ Stake BIO now to stack BioXP and get ready for the first wave of Season 2 Sales. Coming soon!
AI-driven biology is exploding, with giants like Google, OpenAI and Stanford University building scientific agents that read papers, generate hypotheses & design experiments. But these tools remain siloed in Web2 - disconnected from capital, coordination & shared knowledge. BioAgents break these barriers by integrating onchain features for data sharing, experiment funding & discovery monetization. Experiments can start immediately once vetted, rather than languishing in traditional grant cycles, while BioAgents read and write to a decentralized knowledge graph integrated across the Bio network. Stay tuned for more details on the first BioAgent launches, powered by $BIO
AI-driven biology is exploding, with giants like Google, OpenAI and Stanford University building scientific agents that read papers, generate hypotheses & design experiments.

But these tools remain siloed in Web2 - disconnected from capital, coordination & shared knowledge.

BioAgents break these barriers by integrating onchain features for data sharing, experiment funding & discovery monetization.

Experiments can start immediately once vetted, rather than languishing in traditional grant cycles, while BioAgents read and write to a decentralized knowledge graph integrated across the Bio network.

Stay tuned for more details on the first BioAgent launches, powered by $BIO
Science is entering its Agentic Era Introducing the Scientific AI Ecosystem Map! 🗺️ We mapped the tools, models & agentic frameworks powering the new substrate for bio Built to help founders, researchers & builders navigate the explosion in scientific AI Let’s break it down🧵
Science is entering its Agentic Era

Introducing the Scientific AI Ecosystem Map! 🗺️

We mapped the tools, models & agentic frameworks powering the new substrate for bio

Built to help founders, researchers & builders navigate the explosion in scientific AI

Let’s break it down🧵
The fiat system says lose a little of your wealth every year. The medical system says lose a little of your health every year. Crypto and longevity say: what if we reject both? cc @balajis @VitalikButerin @thenetworkstate
The fiat system says lose a little of your wealth every year.

The medical system says lose a little of your health every year.

Crypto and longevity say: what if we reject both?

cc @balajis @VitalikButerin @thenetworkstate
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